SOS2 and hepatocellular carcinoma: Correlation analyses on clinical characteristics and multivariate parameters of 237 HCC patients indicated that SOS2 was an independent prognostic factor associated with both overall survival (OS) (HR = 1.442, P < 0.001) and time to recurrence (TTR) (HR = 1.485, P = 0.029) (Tables S1 and S2).