For instance, the neuron-specific peptide rabies viral glycoprotein (RVG) [78], αγ integrin-specific peptide iRGD [79], and HER2-binding affibody zHER [80] have been anchored on EVs through fusion with Lamp2b to impart EVs with selective migration toward the central nervous system, integrin-positive breast cancer cells, and HER2-expressing tumor cells separately. The gene discussed is ERBB2; the disease is breast carcinoma.