The top 10 pathways with the greatest enrichment were the MAPK signaling pathway, transcriptional mis-regulation in cancer, human T-cell leukemia virus 1 infection, cell adhesion molecules, cytokine-cytokine receptor interaction, Hippo signaling pathway, HIF-1 signaling pathway, TNF signaling pathway, advanced glycation end products, and the receptor for advanced glycation end products (AGE-RAGE) signaling pathway in diabetic complications and cellular senescence. This evidence concerns the gene TNF and cancer.