VIM and infection: Secreted levels of hnRNPA1 and vimentin were increased by 1.8- to 2.7-fold and 1.6- to 5.7-fold, respectively, in C/A and C/S (versus N/H) subjects (P < 0.001) (Fig. 2D and E) and exhibited excellent predictive value in identifying occurrence of infection (area under the receiver operating characteristic [ROC] concentration-time curve [AUC] = 0.953 to 0.986, Cox and Snell R2 [R2C&S] = 0.518 to 0.598) (Fig. 2F and Table 1; see Table S2 in the supplemental material).