CRP and hypertensive disorder: A cross-sectional study that examined the association between CRP levels and HTN in premenopausal, peri-menopausal and postmenopausal women found a nonsignificant, positive association in peri-menopausal and postmenopausal women but a significant positive association in premenopausal women [48], even when adjusting for age and BMI, suggesting the potential role of oestrogen in the sex differences in association.