A recently established OMIM entry (#619075) called Bachmann‐Bupp Syndrome (BABS) is caused by gain‐of‐function variants in the C‐terminus of ODC and is characterized by alopecia, developmental delay, macrosomia, macrocephaly, and some dysmorphic features (Bupp et al., 2018; Rodan et al., 2018). Here, ODC1 is linked to neurodevelopmental disorder with alopecia and brain abnormalities.