It is characterized by the presence of the Philadelphia (Ph) translocation-t (9; 22) (q34; q11), which results in breakpoint cluster region (BCR)/ABL in 5% to 8% of CML cases.[1,2] CML patients frequently present with leukocytosis, although isolated thrombocytosis is rare. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.