IL17A and tuberculosis: The global persistence of M. tb infection over a long time suggests that there is strong evolutionary pressure for the interaction between host and pathogen genomes.[34–36] susceptibility gene polymorphisms interacted by M. tb play a role in the development of TB.[37,38] The GG genotype of IL-17 rs2275913 in the Spanish population is associated with a high risk of tuberculosis,[39] while the CC genotype of rs763780 in the Chinese population increases the risk of tuberculosis.[40] In this study, the proportion of Zhuang population was significantly higher in TB hot spots.