A similar result showed that SNP Rs9272785 for HLA-DQA1 showed a suggestive association in the young-onset Tuberculosis subgroup (onset age 20–40 years, N = 396), although no significant association was found in the entire sample.[41] This result supports the hypothesis that the pathogenesis of TB strains in different age groups and that genetics may play an important role only in the younger onset of TB. This evidence concerns the gene HLA-DQA1 and tuberculosis.