Interestingly, we also found that Tfh cells was positively correlated with activated NK cells (r = 0.299; P < .01), CD8+ T cells (r = 0.25; P < .01), memory activated CD4+ T cells (r = 0.09; P = .048), regulatory T cells (r = 0.16; P < .01), and M1 macrophages (r = 0.28; P < 0.01) in the correlating matrix of all 22 immune cell proportions (Fig. 2) These results further indicate that anti-tumor immunity was activated with greater Tfh cell infiltration. The gene discussed is CD4; the disease is neoplasm.