GRN and Sepsis: In both sepsis groups combined (n = 241), progranulin concentrations were 57.5 ng/ml (Q25–Q75: 42.8–84.9) and significantly higher than in healthy individuals (n = 53) (28.7 ng/ml (Q25–Q75: 25.5–31.7, p < 0.001) (Additional file 1: Table S5).