GSK3B and non-small cell lung carcinoma: In addition, the protein analysis showed that GSK3β and p-β-catenin protein expression levels were increased in NSCLC cells after treatment with SNX-2112, while β-catenin and p-GSK3β levels were decreased, suggesting that SNX-2112 might inhibit the invasion and migration of NSCLC cells by inhibiting the Wnt/β-catenin pathway.