PIK3CA and breast cancer: We identified 13 negatively correlated miRNA-MCM pairs, including hsa-miR-760-MCM1, hsa-miR-1224-5p-MCM1, hsa-miR-4739-MCM1, hsa-miR-139-5p-MCM2, hsa-miR-299-3p-MCM4, hsa-miR-654-5p-MCM4, hsa-miR-140-3p-MCM4, hsa-miR-139-5p-MCM5, hsa-miR-326-MCM5, hsa-miR-654-5p-MCM5, hsa-miR-299-3p-MCM10, hsa-miR-485-3p-MCM10, and hsa-miR-543-MCM10, that may regulate MCM expression in BC and be used to predict the prognosis of BC patients.