As a malignant tumor biomarker, it has high specificity for hepatocellular carcinoma, so it can become the most valuable marker for the diagnosis of liver cancer, contributing to the differentiation of liver disease and the diagnosis of liver cancer.10 GP73 is a transmembrane protein that exists in the Golgi apparatus and is expressed in epithelial cells of various human tissues. This evidence concerns the gene GOLM1 and hepatocellular carcinoma.