CRP and Increased total leukocyte count: Additional factors along with appendicolith presence, causing failure of non operative management include raised CRP, marked leukocytosis (more than 15,000 WBC/μl), bandemia, and extensive disease on CT scans as reported by Howell EC and co-authors.18 In our study, we also established that CRP and raised TLC were significantly associated with failure of conservative management.