Chiral lignan glucosides, (±)-lyoniresinol 3α-O-β-D-glucopyranoside (LGP1 (105) and LGP2 (106)), isolated from A. carambola root have been evaluated for health-promoting properties in LGP1 and LGP2-mediated hypoglycemia against renal injury in STZ-created diabetic mice. This evidence concerns the gene GHDC and Hypoglycemia.