Survival time ↑; tumor growth ↓; TNF-α, IL-6, IL-12, TGF-β, VEGF ↓; Bax, cleaved caspases-3 and -9 ↑; Bcl-2, MMP-2 and -9, NF-κB and IκBα ↓. The gene discussed is BAX; the disease is neoplasm.