Table 1 showed the main characteristics of enrolled patients. Among them, HT occurred in 17 patients (22.37%) within 1 week after reperfusion therapy. Compared with non-HT patients, HT patients had higher median baseline NIHSS score [12 (10.5–18.0) versus 6 (4–12), p = 0.003], and higher mean serum occludin level (5.47 ± 1.25 versus 3.81 ± 1.19, p < 0.001). Here, OCLN is linked to hematocrit.