To assess whether there is a correlation between the CXXC5 and MeCP2 expressions in clinical settings particularly in breast cancer patients that could highlight the importance of our observations, we used the GEPIA (Gene Expression Profiling Interactive Analysis) webserver for the expression analyses of CXXC5 and MeCP2 based on paired normal tissue and tumor samples from the TCGA and healthy tissue samples from the GTEx databases65. The gene discussed is CXXC5; the disease is breast carcinoma.