MECP2 and colon carcinoma: However, our analysis of a recent ChIP-Seq dataset carried out with the use of mouse embryonic stem cells22 suggests, at least in one of two replicates of ChIP-seq results, that CXXC5 may interact with the promoter region of IL12A. Although there is no MeCP2 ChIP-Seq dataset generated with the use of MCF7 cells, analyses with datasets from IMR-90, a human lung fibroblast cell line, and HCT-166 cells derived from human colon carcinoma revealed that MeCP2 could associate with the promoter region of HDAC11, NFKBIZ, or IL12A (Supplementary Information Fig. S9).