Concordantly, the expression of the gene sets upregulated by NAS1 knockdown or NR2F1 overexpression, identified by our transcriptomic sequencing analyses (Supplementary Table 4), was linked to accelerated and decelerated metastasis, respectively, in the Netherlands Cancer Institute breast cancer cohort75 (Fig. 7f, g). Here, NR2F1 is linked to breast carcinoma.