PDC and COVID-19: Having defined in vitro the key role of pDC in the induction of a type I IFN-mediated anti-viral state in SARS-CoV-2-treated human PBMC, we then moved to study this cell type ex vivo in PBMC collected from individuals with asymptomatic SARS-CoV-2 infection (CP-AS, n = 8), in hospitalized COVID-19 patients (CP, n = 6) and in a cohort of healthy donors matched for sex and age (HD, n = 5) (see gating strategy in S6A Fig and patient characteristics in S2 and S3 Tables).