ANXA5 and infection: Infection with the staphopain A mutant led to significantly fewer annexin V+/7AAD+ cells six hours post-infection as when compared to the wild type, whereas no difference in annexin V+/7AAD+ cells could be detected between infection with scpA mutant and Cowan I. The amount of annexin V+/7AAD- and annexin V-/7AAD+ cells did not reveal any difference between infection with JE2, the scpA mutant or Cowan I. This observation indicates a late apoptotic or necrotic behavior of JE2-infected cells at six hours post-infection.