CXCL12 and colon adenocarcinoma: Results also revealed that down-regulation of CXCL12 [HR: 1.1, p>0.05] and up-regulations of CXCL8 [HR: 0.61, p>0.05], AGT [HR: 0.64, p>0.05], GNB1 [HR: 0.57, p<0.05], and, CXCL1 [HR: 0.69, p<0.05] are the bad prognostic biomarkers for predicting the OS duration of the COAD patients as they do not correlated with the reduced OS duration (Fig 13).