The typical diagnostic imaging of PD includes dopamine transporter (DAT)-SPECT with 123I-ioflupane detecting decreased accumulation in the striatum, and myocardial perfusion scintigraphy with the noradrenaline analogue 123I-metaiodobenzylguanidine (MIBG) also detecting decreased accumulation. The gene discussed is SLC6A3; the disease is Parkinson disease.