VEGFA and endothelial dysfunction: In pre‐eclampsia with endothelial dysfunctions, another condition under VEGF signaling inhibition (Butler et al., 2020; Jourde‐Chiche et al., 2019; Levine et al., 2004; Moghaddas Sani et al., 2019) due to anti‐angiogenic factor, soluble fms‐like tyrosine kinase 1 produced by diseased placenta, and inflammation, serum levels of hyaluronan were significantly increased in our analyses (Figure 5C), supporting previous reports (Weissgerber et al., 2019; Ziganshina et al., 2020).