Cox analysis showed that ASF1B expression was significantly correlated with OS in ACC (p < 0.001), CESC (p < 0.001), DLBC (p = 0.042), KICH (p < 0.001), KIRC (p < 0.001), KIRP (p < 0.001), acute myeloid leukemia (LAML) (p = 0.035), lower grade glioma (LGG) (p < 0.001), LIHC (p = 0.001), LUAD (p = 0.003), mesothelioma (MESO) (p < 0.001), PAAD (p < 0.001), PCPG (p = 0.004), STAD (p = 0.028), THCA (p = 0.037), THYM (p = 0.023), and uveal melanoma (UVM) (p =< 0.022) (Figure 2A). Here, ASF1B is linked to central nervous system cancer.