In addition, miR-494-3p also regulates the expression of DAG1 gene encoding dystroglycan which is the central component of dystrophin–glycoprotein complex, TNPO3 gene encoding Transportin-3 which usually found in its mutated form in LGMD, DNAJB6 gene which also the one of the main causes of LGMD, and miR-494-3p is also regulating TOR1AIP1 or Lamin-associated protein 1B. The gene discussed is TNPO3; the disease is limb-girdle muscular dystrophy.