HMOX1 and glioblastoma: The obtainedcompounds (Table 1)behaving as potent HO-1 inhibitors have been screened for their antiproliferativeactivity and HO-1 expression levels against a small panel of cancercell lines, showing the best activity toward the GBM cell line U87MG.This exploration also identified compound 7l as suitablefor further investigating its in-cell enzymatic HO-1 activity andits effects on cell invasion.