It does not only lower blood sugar by enhancing insulin sensitivity, promoting insulin secretion, protecting islet cells, stimulating glycolysis in peripheral tissue cells, inhibiting gluconeogenesis in the liver, and anti-insulin resistance (IR) but also improves the symptoms of inflammation, oxidative stress, and lipid metabolism disorders in diabetic patients by anti-inflammatory, antioxidant, antiapoptotic, and lipid metabolism disorder regulation. This evidence concerns the gene INS and Insulin resistance.