According to the results of the univariate analysis, unfavorable outcomes were closely associated with male sex, type of cancer, systemic metastasis, adenocarcinoma, the initial NIHSS score, thrombolytic therapy, hemoglobin A1c level, fasting glucose level, high-sensitivity C-reactive protein (hs-CRP) level, D-dimer level, multiple territory lesions, subcortical WMH, SBI, and CMBs (Table 3). The gene discussed is CRP; the disease is cancer.