Chi-squared tests showed that the high expression of PD-L1 (tumor proportion score [TPS] of ≥ 50%) was more common in male patients, smokers, the histological type of SCC and other in NSCLC, pathological stage II and IIIA, the presence of adjuvant therapy, and wild-type EGFR mutation status. Here, CD274 is linked to non-small cell lung carcinoma.