Notably, if only the sham-operated and the CKD groups were compared by unpaired t-test, the left ventricular β3-AR mRNA expression was significantly increased in the CKD group compared to the sham-operated group (0.99 ± 0.07 vs. 0.65 ± 0.10 relative gene expression, p = 0.012). This evidence concerns the gene ADRB3 and chronic kidney disease.