Because the αV subunit pairs with β6 and β8 subunits to activate TGF-β26, we first conducted quantitative (q)RT-PCR to evaluate the expression of ITGAV, ITGB6, and ITGB8 mRNA in 15 freshly resected primary NSCLC. This evidence concerns the gene ITGB6 and non-small cell lung carcinoma.