According to the GEPIA and TIMER databases, PPM1D mRNA expression in HCC tissue remarkably associated with the expression of marker gene due to TAMs, tumor-infiltrating Monocytes, M1 Macrophage, M2 Macrophage, DCs, Th and Treg (Figure 4 and Table 4), while the association was not remarkable in CHOL (Supplementary Figure 3 and Table 4). The gene discussed is PPM1D; the disease is neoplasm.