Notably, patients with no response to chemoradiotherapy (red circles) displayed significantly higher proportions of Th17 cells in their tumor tissues (Fig. 4FG; P = 0.0026, P = 0.0009) and higher scores of pretherapeutic pThr308‐ (Fig. 4H; P = 0.0004) or pSer473‐AKT expression (Fig. 4I; P = 0.0004) in neoplastic cells than patients with only partial response to therapy (orange circles). The gene discussed is AKT1; the disease is neoplasm.