Patients with type 2 diabetes who required basal insulin therapy (IRR, 0.69; 95% CI, 0.63-0.75) or no insulin therapy (IRR, 0.36; 95% CI, 0.33-0.40) had a lower risk of hyperglycemic crises compared with those treated with bolus, with or without basal, insulin therapy. Here, INS is linked to type 2 diabetes mellitus.