For both patients with type 1 diabetes and those with type 2 diabetes, rates of hyperglycemic crises were highest among younger patients, Black patients, patients with lower income, women, and (for type 2 diabetes) patients requiring insulin therapy (Figure 1 and Figure 2 and eTable 5 and eTable 6 in the Supplement). The gene discussed is INS; the disease is type 2 diabetes mellitus.