In our case–control study, we evaluated the impact of single nucleotide polymorphisms rs1047972, rs2273535, rs8173 and rs911160 (AURKA), rs2289590 and rs2241909 (AURKB), rs11084490 and rs758099 (AURKC) and rs42873 (PLK1) in mitotic checkpoint genes on glioblastoma multiforme development in Bosnia and Herzegovina population. The gene discussed is AURKB; the disease is glioblastoma.