TMPRSS2 and COVID-19: In the present study, the rs6020298 in TMEM189-UBE2V was not associated with COVID-19 severity (P = 0.72, OR = 0.97 for A allele), while the rs12329760 in TMPRSS2 showed a nominal association (P = 0.010, OR = 0.81 for T allele) (Supplementary Table S11).