ACADVL and very long chain acyl-CoA dehydrogenase deficiency: Very long-chain acyl-coenzyme-A dehydrogenase deficiency (VLCADD) is caused by pathogenic mutations in ACADVL gene, with an incidence range of 1/380,000–1/1,400,000 in Asian region, and hundreds of pathogenic mutations have been reported so far [3–8].