IL6 and obesity due to melanocortin 4 receptor deficiency: In addition, when looking into putative differences in the neurogenic response to IL6 comparing obesity-prone (H) and obesity-resistant (L) mice (described in “In vivo protocol #2”), we found that ip IL6 promoted a significantly larger expression of Sox6 transcripts (Fig. 5D) and a trend for increase of doublecortin transcripts (Fig. 5E) in obesity-resistant mice.