The results of GO analysis showed that these co-expressed genes were mainly enriched in the following: oxidation-reduction process, regulation of cellular amino acid metabolic process, glutathione metabolic process, ER to Golgi vesicle-mediated transport, COPII vesicle coating, NIK/NF-kappaβ signaling, endoplasmic reticulum, endoplasmic reticulum, mitochondrial inner membrane, and Golgi membrane which is in consistent with the previous results that the SRD5A3 protein expression is located in cytoplasm and cell membrane in human tumor cells (Table 5). This evidence concerns the gene SRD5A3 and neoplasm.