TP53 and colorectal carcinoma: Immunohistochemical investigation of tumorigenic pathways in SBA and CRC revealed that positive β-catenin expression is less frequent in SBA (19.2 to 19.6%) than in CRC (78.6%), although the proportion of patients with high TP53 expression in SBA (41.6 to 53.8%) is similar to that in CRC (43.5%) and the proportion of patients with MMRD in SBA (8.0 to 23.0%) is similar to that in CRC (12.5%) [27–29].