In agreement with the collective behavior of IgA-related genes, we found no difference in IgA levels between the KS2 and wild-type, while we recapitulated our previous result of IgA deficiency in KS1 mice (Pilarowski et al., 2020; Figure 5E; p = 0.8 for KS2 vs. WT, p = 0.0008 for KS1 vs. WT, Figure 5—source data 3). Here, CD79A is linked to hyperinsulinemic hypoglycemia, familial, 4.