This study was unique in that researchers examined patients aged 75 years or older who met AML clinical trial inclusion criteria of PS 0–2, glomerular filtration rate at or below 60 ml/min, alanine transaminase at or below twice the upper limit of normal, bilirubin ≤ 1.5 mg/dl, and measures of cardiac health including no history of myocardial infarction, congestive heart failure, or left ventricular ejection fraction below 49%, suggesting that clinicians were more likely to treat patients that met IC treatment criteria (Percival et al. 2019). Here, GPT is linked to congestive heart failure.