ARG1 and myocardial infarction: Additionally, we also measured the expression of iNOS and Arg1 protein in the myocardium at 7 days post-MI, and we found that (Figure 4) the number of M1 macrophages (iNOS+F4/80+ cells) in the myocardium of MI mice without any treatment at 7 days post-MI was significantly higher than that in the myocardium of MI mice treated with curcumin at 7 days post-MI, while the number of M2 macrophages (Arg+F4/80+ cells) was significantly lower.