ITGAX and colitis: Deletion of Zbp1 partially restored sensitivity to DSS in CD11c;Ripk1kd/kd;Zbp1−/− mice, although these mice were still significantly protected from DSS when compared to Ripk1kd/kd;Zbp1−/− mice (Fig. 6e), suggesting that ZBP1 might have a minor contribution to the protective effect of DC-specific RIPK1 deletion on DSS-induced colitis.