Clusterin (CLU), FN1, glycerol, hyaluronan binding protein 2 (HABP2), insulin like growth factor 2 (IGF2), kininogen 1 (KNG1), l-glutamic acid, protein S (PROS1), serpin family C member 1 (SERPINC1), and serpin family F member 1 (SERPINF1) are involved in the growth of epithelial tissue-related processes, predicted to be activated in MCO compared to levels in the 1stst HF (activation z-score = 1.913). This evidence concerns the gene PROS1 and hydrops fetalis.