The orthotopic prostate tumors were probed with antibodies against NuMA (Figs. 3f and 4f), Lamin A + C (Figs. 3g and 4f), and CD44 (Fig. 3h) or prostate-specific membrane antigen (PSMA; Fig. 4f), to distinguish between cells of human and murine origin. Here, CD44 is linked to prostate neoplasm.