There was a significant decrease in the levels of anti-inflammatory factors IL-1ra (p < 0.04); IL-10 (p < 0.0001); adiponectin (p < 0.0001); adiponectin/leptin ratio (p < 0.0001) and anti-fibrotic Klotho (p < 0.0001); relaxin-1 (p < 0.0001); relaxin-3 (p < 0.0001) in older adults with MS compared to without MS. This evidence concerns the gene RLN1 and myeloid sarcoma.