The results demonstrate increased levels of pro-inflammatory mediators in the participants with MS IL-1beta (p < 0.0001); IL-8 (p < 0.0001); TNF-alpha (p < 0.0001); leptin (p < 0.0001) and pro-fibrotic VEGF (p < 0.0001) compared to those without MS. This evidence concerns the gene LEP and myeloid sarcoma.