VAV2 and esophageal squamous cell carcinoma: In addition, the STAT1 levels were positively correlated with the levels of VAV2 in ten ESCC cell lines (r = 0.734, P = 0.0156; Supplementary Fig. S5g) and were substantially higher in IR-induced radioresistant KYSE150 and KYSE450 cells having high VAV2 expression compared with that in the parental cells having lower VAV2 expression and sensitive to IR (Fig. 5d).