VAV2 and cancer: We investigated the survival association of VAV2 mRNA levels in TCGA patients who were treated with radiotherapy and had survival data (n = 2390 of 20 cancer types) and the results showed that patients (n = 1195) having the VAV2 mRNA level > 1144 (median) in tumor had an HR of 1.20 (95% CI = 1.02–1.41, P = 0.028) for death compared with those (n = 1195) having the VAV2 mRNA level ≤ 1144, adjusted for age, sex, tumor stage, and tumor type (Supplementary Table S7).