We also detected positive correlations between VAV2 and STAT1 RNA levels in our previous study samples (r = 0.375, P = 0.0002, n = 94; Fig. 5e) and TCGA ESCC dataset (r = 0.301, P = 0.0032, n = 94; Supplementary Fig. S5h) and protein levels in ESCC samples (r = 0.332, P < 0.0001, n = 240; Supplementary Fig. S5i). Here, STAT1 is linked to esophageal squamous cell carcinoma.