Interestingly, we found that BCOR mutations were frequently associated with mutations in ASXL1/DNMT3A and TET2 but not in RUNX1 (p = 0.822) (Fig. 1b); the p value for the association between BCOR and RUNX1 mutations was 0.002 as reported by Frederik Damm et al. [8], which was not similar to that for ASXL1/DNMT3A and TET2, which play initial roles in the origins of MDS [16] and also not similar to U2AF1/RUNX1 and TP53, which are linked with unique abnormal chromosomes [17–19] (trisomy 8; chromosome 7 involvement; and complex karyotypes). This evidence concerns the gene ASXL1 and myelodysplastic syndrome.