We analyzed the top ten genes which had the highest co-amplification frequencies with LANCL2 or EGFR. Results indicated that the amplification frequencies of EGFR, SEC61G and VOPP1 genes were the top three highest in LANCL2-amplified GBM samples, while SEC61G, LANCL2 and VSTM2A were the top three genes co-amplified with EGFR (Fig. 1G). This evidence concerns the gene VOPP1 and glioblastoma.