Results found that only age and gender had a significant impact on OS of IDH1/2-wild-type GBM patients, whereas LANCL2 or EGFR amplification and their co-amplification were not significantly correlated with OS and PFS of IDH1/2-wild-type GBM patients (Additional file 1: Figure S1D, Tables S2, S3). The gene discussed is EGFR; the disease is glioblastoma.